- Subject index
With escalating healthcare costs, changes to the regulatory control on pharmaceutical industries and the inevitable adjustments made in policies and investment in healthcare there is enormous interest in the commercial as well as the scientific aspects of today's healthcare industry.
The SAGE Handbook of Healthcare provides an authoritative analysis of the current (and anticipated) developments in the global healthcare industries. Providing a unique perspective that interfaces between the science and business aspects, it combines information on the latest scientific developments with applied, commercial business data from the global marketplace.
The Handbook focuses on the aspects of paramount importance in the healthcare sector: Pharmacoeconomics; Pharmacogenomics; Therapeutics; Diagnostics
Areas covered include: The role of nanotechnology, genomics and cell therapy in medicine; Diagnostics; Biomarkers and technological advances; Case studies in oncology ...
Chapter 26: Outlook for Cancer Vaccine Development
Outlook for Cancer Vaccine Development
An Era of Change for Cancer Therapy
With the rapid incorporation of monoclonal antibodies (MAbs) into oncology therapy, an environment of acceptance of new biologic therapies – including cancer vaccines – as a viable therapeutic approach is forming. Genentech and ImClone's highly visible and successful 2004 MAb launches (bevacizumab [Avastin] and cetuximab [Erbitux], respectively) have increased anticipation for the next new therapy. Although Dendreon's long-awaited cancer vaccine, Provenge, has not yet delivered on earlier expectations, several vaccines, specifically Merck's Gardasil and GlaxoSmithKline's Cervarix, are rapidly approaching their filing dates and have the potential to initiate the therapeutic acceptance of cancer vaccines.
The gold standard for cancer treatment remains chemotherapy, but combination therapy, particularly combining chemotherapy agents with biologies, ...