Corpus Callosum

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  • A structure that connects the left and right cerebral hemispheres. It is a 4-inch-long, ¼-inch-thick structure that consists of millions of flat bundle axons. The corpus callosum is the largest white matter brain structure and is responsible for most of the interhemispheric brain communication. When the corpus callosum is severed, patients experience different degrees of “disconnection,” known as a split-brain condition. A surgical operation conducted to separate the two hemispheres (corpus callosotomy) is rarely performed as a last resort in intractable epilepsy.

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