This entry describes the racial/ethnic disparities in HIV infection among gay, bisexual, and other men who have sex with men (GBMSM). The entry begins with an overview of epidemiological trends in HIV infection across race/ethnicity. Next, it leads into a discussion on factors contributing to the disproportionate rates of HIV infection among Black and Latino GBMSM, with a particular focus on Black GBMSM, as this population suffers the heaviest burden of HIV. These factors will be explored across multiple socioecological levels, including individual, community, and sociostructural levels. The entry concludes with a brief discussion on current avenues for culturally mediated approaches to public health intervention.