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The American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), describes substance use disorders related to nine different classes of drugs. Hallucinogens such as phencyclidines account for one of these drug classes. The traditional phencyclidines with which the lay public is most familiar are 1-(1-phencyclohexyl) piperidine (PCP) and the similarly acting compound ketamine. With the explosion of the designer drug market over the past decade, various phencyclidine analogs are being used by persons worldwide (a phencyclidine analog is a human-made drug intentionally created to mimic more traditional phencyclidines for the purpose of evading drug laws—the creation of such compounds from various drug classes is the basis of the designer drug industry).

Phencyclidine use disorder is defined in the DSM-5 as a problematic ...

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